經歷
輔英技術學院 保健營養系 助理教授
私立中原大學 生物科技學系 助理教授
私立中原大學 生物科技學系 副教授
現職
生科系教授
奈米科技中心副主任
專長
細胞生物學Cell biology
訊息傳遞調控Signal transduction
研究領域
細胞生物學
訊息傳遞調控
可能之應用
探討細胞凋亡的機制,進而瞭解一些抗凋亡天然物的作用機制。(To study the regulatory mechanisms of anti-apoptosis compounds)
尋找誘發癌細胞凋亡的藥物或化合物,並瞭解其訊息傳遞的機制。(To search the natural apoptotic inducer compounds for cancer therapy
)
個人研究成果 (Selected paper 5 篇 )
1. Chan, W.-H . , Yu, J.-S., and Yang, S.-D. (2000)
Apoptotic signalling cascade in photosensitized human epidermal carcinoma cells: Involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3, and p21-Activated kinase 2
Biochem. J. 351, 221-232. (SCI)
(NSC-88-2314-B-182-036 and NSC-89-2316-B-182-005)
2. Chan, W.-H. * , Wu, C.-C., and Yu, J.-S. (2003)
Curcumin Inhibits UV Irradiation-induced Oxidative Stress and Apoptotic Biochemical Changes in Human Epidermoid Carcinoma A431 Cells
J. Cell. Biochem. 90:327-338 (SCI) ( *correspondence author)(NSC 90-2315-B-242-001 and NSC91-2320-B-033-005)
3. Chan, W.-H. * and Wu, H.-J. (2004)
Antiapoptotic Effects of Curcumin on Photosensitized Human Epidermal Carcinoma A431 CellsJ. Cell. Biochem. 92: 200-212 (SCI) (*correspondence author)
(NSC91-2320-B-033-005 and NSC92-2320-B-033-003)
4. Chan, W.-H. * (2005)
Effect of Resveratrol on High Glucose-Induced Stress in Human Leukemia K562 Cells.
J. Cell. Biochem. 94: 1267-1279 (SCI) (NSC93-2320-B-033 -003 and NSC 93-2120-M-033-001 )
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